Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Intranasal opioids for acute pain].

C Añez Simón1, M Rull Bartomeu, A Rodríguez Pérez

  • 1Servicio de Anestesiología, Reanimación y Terapéutica del Dolor y M. Paliativa, Hospital Universitario de Tarragona Joan XXIII, Tarragona. cristobal_anez@yahoo.es

Revista Espanola De Anestesiologia Y Reanimacion
|February 17, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic factors and oncological outcomes after trimodality bladder-preserving therapy for muscle-invasive bladder cancer: A multicenter real-world study.

Actas urologicas espanolas·2026
Same author

RENORT: a project to analyze patterns of care in radiation oncology in Spain.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2022
Same author

Longitudinal Flow Decorrelations in Xe+Xe Collisions at sqrt[s_{NN}]=5.44  TeV with the ATLAS Detector.

Physical review letters·2021
Same author

Measurement of the Lund Jet Plane Using Charged Particles in 13 TeV Proton-Proton Collisions with the ATLAS Detector.

Physical review letters·2020
Same author

Cellular immunotherapy: a clinical state-of-the-art of a new paradigm for cancer treatment.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2020
Same author

Measurement of Azimuthal Anisotropy of Muons from Charm and Bottom Hadrons in pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

Physical review letters·2020

Intranasal drug delivery offers a noninvasive route for pain management, bypassing liver metabolism. This review examines opioids like fentanyl for acute pain, noting similar side effects to IV routes.

Area of Science:

  • Pharmacology
  • Drug Delivery Systems
  • Pain Management

Context:

  • Intranasal drug administration presents a noninvasive, well-tolerated transmucosal route.
  • The nasal mucosa offers a large, vascularized surface area for drug absorption.
  • Mucociliary clearance and physiological factors influence drug contact time and absorption.

Purpose:

  • To review the literature on intranasal administration of specific opioids for acute pain.
  • To evaluate the efficacy and safety of intranasal opioids compared to intravenous administration.

Summary:

  • Opioids including fentanyl, meperidine, diamorphine, and butorphanol were reviewed for intranasal administration in acute pain.
  • Adverse systemic effects mirror those of intravenous administration, commonly including drowsiness, nausea, and vomiting.

Related Experiment Videos

  • Local adverse effects such as a burning sensation and bad taste were also reported.

    • Impact:

    • Intranasal opioid administration is a viable alternative for managing acute pain.
    • Understanding absorption dynamics and potential side effects is crucial for clinical application.
    • This route may offer advantages in specific patient populations or clinical scenarios.