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Updated: Jul 16, 2026
08:03
Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Craniofacial fibrous dysplasia: an update
Yu-Ray Chen1, Cheng-Nen Chang, Ying-Chien Tan
1Chang Gung Craniofacial Center, Chang Gung Memorial Hospital, Gueishan Shiang, Taoyuan, Taiwan 333, R.O.C. uraychen@cgmh.org.tw
Chang Gung Medical Journal
|February 17, 2007
Summary
Fibrous dysplasia, a benign bone tumor, can cause significant facial disfigurement and vision loss. Recent studies question the necessity of prophylactic optic nerve decompression for optic canal involvement.
Area of Science:
- Orthopedics
- Neurosurgery
- Pathology
Background:
- Fibrous dysplasia is a benign bone disorder characterized by the replacement of normal bone with fibrous tissue.
- It primarily affects the craniofacial skeleton, leading to cosmetic and functional impairments.
- Optic nerve compression causing visual impairment is a critical complication.
Purpose of the Study:
- To review the current understanding of fibrous dysplasia.
- To evaluate the effectiveness and necessity of prophylactic optic nerve decompression in cases of optic canal involvement.
Main Methods:
- Review of recent literature on fibrous dysplasia.
- Analysis of imaging characteristics and treatment outcomes.
- Evaluation of studies questioning prophylactic optic nerve decompression.
Main Results:
- Fibrous dysplasia management presents surgical challenges.
- Recent research has improved understanding of its etiology and behavior.
- Emerging evidence challenges the routine use of prophylactic optic nerve decompression.
Conclusions:
- Further research is needed to clarify the role of prophylactic optic nerve decompression.
- Optimizing treatment for fibrous dysplasia remains an ongoing goal.
- The management of fibrous dysplasia requires careful consideration of potential complications and treatment efficacy.
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