Convenient numerical procedures for estimating cumulative pregnancy curves
1Department of Obstetrics and Gynecology, University of Pittsburgh School of Medicine, Pennsylvania.
Fertility and Sterility
|January 1, 1992
Summary
A new estimation procedure ensures convergence for cumulative pregnancy models. Laser laparoscopy for endometriosis achieved a 56% cure rate and a 9.7% monthly pregnancy probability in cured patients.
Area of Science:
- Reproductive Medicine
- Biostatistics
Background:
- Estimating cumulative pregnancy curves is crucial for assessing infertility treatments.
- Previous two-parameter models have faced convergence issues, hindering accurate analysis.
- Endometriosis affects fertility, necessitating effective treatment and outcome assessment.
Purpose of the Study:
- To develop a robust and simple estimation procedure for a two-parameter cumulative pregnancy model.
- To ensure consistent convergence on a solution for pregnancy curve analysis.
- To provide a reliable method for evaluating infertility treatment outcomes.
Main Methods:
- Utilized raw data from a prior study where the two-parameter model failed to converge.
- Developed and applied a new computer-based estimation procedure.
- Analyzed pregnancy outcomes and model convergence in infertile women with endometriosis.
Main Results:
- The novel estimation procedure successfully converged on a solution.
- Laser laparoscopy demonstrated a 56% cure rate across all endometriosis stages.
- The monthly probability of pregnancy among cured patients was 9.7%.
Conclusions:
- The developed personal computer program offers a user-friendly and consistently converging solution for the two-parameter cumulative pregnancy model.
- This method enhances the analysis of pregnancy rates following infertility treatments.
- The findings support laser laparoscopy as a viable treatment for endometriosis-related infertility.
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