Related Experiment Video
Updated: Jul 16, 2026

Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
Breath analysis: the approach towards clinical applications
Anton Amann1, Patrik Spanĕl, David Smith
1Department of Anaesthesia and General Intensive Care, Innsbruck Medical University, Anichstrasse 35, A-6020 Innsbruck, Austria. anton.amann@uibk.ac.at
Exhaled breath analysis offers a non-invasive method for clinical diagnosis and monitoring treatment effectiveness. This technique leverages chemistry and physics for future medical applications.
Area of Science:
- Biomedical Engineering
- Analytical Chemistry
- Clinical Diagnostics
Background:
- Exhaled breath analysis is an emerging non-invasive diagnostic tool.
- Current methods face challenges in specificity and sensitivity.
- Understanding the underlying chemical and physical principles is crucial for advancement.
Purpose of the Study:
- To provide a comprehensive overview of exhaled breath analysis techniques.
- To discuss the chemical and physical principles governing breath analysis.
- To outline current research and future prospects.
Main Methods:
- Review of existing literature on exhaled breath analysis.
- Discussion of analytical techniques (e.g., spectroscopy, chromatography).
- Exploration of the physical and chemical basis of volatile organic compound detection.
Main Results:
- Exhaled breath contains biomarkers indicative of various physiological and pathological states.
- Diverse analytical techniques are being developed and refined for breath analysis.
- Significant progress has been made in identifying specific breath biomarkers.
Conclusions:
- Exhaled breath analysis holds great potential for non-invasive clinical diagnosis.
- Further research is needed to optimize techniques and validate biomarkers.
- This non-invasive approach promises to revolutionize patient monitoring and disease detection.
Related Concept Videos
Assessment of Respiration
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like asthma or COPD,...
Respiratory Assessment: Purpose and Indications
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Assessment of Diffusion and Perfusion
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Physical Assessment of the Respiratory Tract II: Inspection
Chest Configuration
The chest configuration can...
Assessment of Airway, Skin Color, and Use of Accessory Muscles
Introduction
The initial evaluation of a patient's respiratory system...
