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[Pertussis in practice in 2007].

E Grimprel1

  • 1Consultation, urgences pédiatriques, pathologie infectieuse et tropicale, hôpital d'enfants Armand-Trousseau, 26, avenue du Docteur-Arnold-Netter, 75571 Paris cedex 12, France. emmanuel.grimprel@trs.aphp.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|February 20, 2007
PubMed
Summary

Universal infant pertussis vaccination has shifted disease prevalence to adolescents and adults. Boosting vaccination in older age groups and improving physician diagnosis are crucial for controlling Bordetella pertussis transmission and protecting infants.

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Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Public Health

Context:

  • Universal infant pertussis vaccination has altered disease epidemiology.
  • Pertussis (whooping cough) is now frequently observed, though often undiagnosed, in adolescents and adults.
  • This contributes to ongoing Bordetella pertussis transmission in France, risking infant exposure.

Purpose:

  • To analyze the current epidemiology of pertussis in France.
  • To propose strategies for controlling pertussis transmission.
  • To highlight the importance of recognizing and treating pertussis in older populations.

Summary:

  • Pertussis epidemiology has shifted due to widespread infant vaccination, with increased incidence in adolescents and adults.
  • Physician education is needed for early diagnosis of persistent cough in adults and for implementing control measures like antibiotics and revaccination.

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  • While treatment has limited impact on symptoms, it is effective in reducing transmission, with macrolides being the recommended therapy.

    • Impact:

    • Reinforcing vaccination with late boosters in adolescents and adults is essential.
    • Enhanced physician awareness and prompt treatment can curb Bordetella pertussis spread.
    • Protecting vulnerable young infants from severe pertussis requires a multi-faceted control strategy.