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Immittance measures in individuals with Moebius Sequence.

Mariana Cabral de Albuquerque Bezerra1, Silvana Maria Sobral Griz, Graziela de Souza Azevedo

  • 1Clinical Audiology, UFPE, FIR.

Brazilian Journal of Otorhinolaryngology
|February 20, 2007
PubMed
Summary

Acoustic reflexes in Moebius Sequence patients showed varied results, with normal tympanometry but absent ipsilateral reflexes in most. This suggests acoustic reflex testing may aid in predicting VII cranial nerve involvement.

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Area of Science:

  • Neurology
  • Otolaryngology
  • Genetics

Background:

  • Moebius Sequence is a rare congenital disorder affecting cranial nerves VI and VII, leading to facial palsy.
  • Acoustic reflexes involve the stapedius muscle, innervated by the VII cranial nerve.
  • Typically, individuals with Moebius Sequence are expected to have absent acoustic reflexes.

Purpose of the Study:

  • To investigate and describe immittance findings, specifically acoustic reflexes, in a cohort of individuals diagnosed with Moebius Sequence.

Main Methods:

  • Otoscopy and immittance measurements were performed on 17 patients (ages 3-13) with Moebius Sequence.
  • Analysis focused on tympanometry and ipsilateral/contralateral acoustic reflexes.

Main Results:

  • The majority of ears exhibited Type A tympanometry, indicating normal stapedius muscle function.
  • Contralateral acoustic reflexes were present in 50% of the ears studied.
  • Ipsilateral acoustic reflexes were absent in most of the analyzed ears.

Conclusions:

  • The presence of acoustic reflexes in some Moebius Sequence patients suggests potential utility in assessing VII cranial nerve function.
  • Acoustic reflex testing may offer prognostic value for VII cranial nerve lesions in Moebius Sequence.