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Lung cancer in patients with tuberculosis
Saulius Cicenas1, Vladislavas Vencevicius
1Department of Thoracic Surgery and Oncology, Institute of Oncology, Vilnius University, Santariskiu 1, Vilnius, Lithuania. saulius.cicenas@loc.lt
World Journal of Surgical Oncology
|February 21, 2007
Summary
Coexistent lung cancer and tuberculosis is rare in thoracic surgery, affecting 2.1% of patients. Surgery is the preferred treatment, with a median survival of 28 months for these complex cases.
Area of Science:
- Thoracic Surgery
- Oncology
- Pulmonology
Background:
- Coexistent lung cancer and pulmonary tuberculosis presents a significant challenge in thoracic surgery.
- The diagnosis and surgical treatment of this dual condition require specialized approaches.
Purpose of the Study:
- To analyze the incidence, characteristics, and outcomes of patients with coexistent lung cancer and tuberculosis undergoing surgical treatment.
- To evaluate the efficacy of surgical intervention for this rare comorbidity.
Main Methods:
- Retrospective analysis of 2218 lung cancer patients treated surgically between 1990 and 2005.
- Identification of 46 patients (2.1%) with coexistent lung cancer and tuberculosis.
- Detailed review of cancer type, stage, surgical procedures, and postoperative outcomes.
Main Results:
- Epidermoid carcinoma (52.2%) and Stage IIIA disease (50%) were most common.
- Pneumonectomy (39.2%) was the most frequent surgical procedure.
- Postoperative complications occurred in 19.5% of patients, with an overall mortality rate of 13%.
Conclusions:
- The coexistence of lung cancer and tuberculosis is uncommon but poses significant surgical challenges.
- Surgery remains the primary treatment modality for this combined condition.
- Median survival for patients with coexistent lung cancer and tuberculosis treated surgically was 28 ± 2 months.
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