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Updated: Jul 16, 2026

Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia
Published on: April 7, 2023
Dietary plant sterols and cholesterol metabolism
Lars H Ellegård1, Susan W Andersson, A Lena Normén
1Department of Clinical Nutrition, Sahlgrenska Academy at Göteborg University, Box 459, SE-413 90 Göteborg, Sweden Lasse.Ellegard@nutrition.gu.se
Abstract:
Plant sterols, naturally occurring in foods of plant origin, reduce cholesterol absorption. Experimental studies show plant sterols to be an important part of the serum-cholesterol lowering effect of certain diets and dietary components. Epidemiological data show that individuals with higher intakes of plant sterols from their habitual diets have lower serum-cholesterol levels. To date, the role of naturally occurring plant sterols for lowering serum cholesterol has probably been underestimated. The consumption of dietary plant sterols should be a part of dietary advice to patients with hypercholesterolemia and the general public for the prevention and management of coronary heart disease.
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