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Related Experiment Videos

Physiologic motion after vocal cord reinnervation: a preliminary study.

D C Green1, G S Berke, M C Graves

  • 1Division of Head and Neck Surgery, UCLA School of Medicine.

The Laryngoscope
|January 1, 1992
PubMed
Summary

This study achieved physiologic vocal cord motion in a reinnervated vocal cord by targeting the recurrent laryngeal nerve. The technique successfully restored natural vocal cord movement and electromyographic activity.

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Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Regenerative Medicine

Background:

  • Vocal cord paralysis often leads to synkinesis, impairing natural vocal cord motion.
  • Restoring physiologic movement is crucial for improving voice and airway function after nerve injury.

Purpose of the Study:

  • To reestablish physiologic vocal cord motion, not synkinesis, in a reinnervated vocal cord.
  • To evaluate a novel surgical technique for laryngeal reinnervation.

Main Methods:

  • A mongrel dog model was used, involving division and reanastomosis of the recurrent laryngeal nerve's anterior branch.
  • A posterior nerve-muscle pedicle was separated and reimplanted into the posterior cricoarytenoid muscle.
  • Physiologic motion, electromyographic (EMG) activity, acoustic measures, and histologic data were assessed after 21 weeks.

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Main Results:

  • Spontaneous, physiologic vocal cord movement was observed during respiratory obstruction and laryngeal stimulation.
  • Electromyographic (EMG) activity confirmed reinnervation and functional recovery.
  • Histologic and acoustic data supported the successful restoration of vocal cord function.

Conclusions:

  • The described surgical technique can achieve physiologic vocal cord motion after laryngeal reinnervation.
  • This approach offers a promising strategy for treating vocal cord dysfunction and paralysis.