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Stacking interactions as the principal design element in acyl-transfer catalysts

Yin Wei1, Ingmar Held, Hendrik Zipse

  • 1Department Chemie und Biochemie, LMU München, Butenandtstrasse 5-13, D-81377, München, Germany.

Organic & Biomolecular Chemistry
|February 23, 2007
PubMed
Summary

Stacking interactions significantly influence the stability and shape of acylpyridinium intermediates during pyridine-catalyzed acylation reactions. These findings are crucial for understanding reaction mechanisms.

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