Related Experiment Video
Updated: Jul 16, 2026
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
A new approach to label sentinel nodes in endometrial cancer
C Altgassen1, J Pagenstecher, D Hornung
1University of Schleswig-Holstein, Department of Obstetrics and Gynecology, Campus Luebeck, Ratzeburger Allee 160, D-23538 Luebeck, Germany. altgassen@frauenklinik.uni-luebeck.de
Purpose:
The objective of the study was to determine the feasibility of a new method of labeling sentinel lymph nodes in patients with endometrial cancer using blue dye.
Patients And Methods:
4 ml of blue dye was subserously administered in 25 patients with endometrial cancer at eight sites. After 8 min, sentinel lymph nodes were harvested.
Results:
Detection rate was 92.0%, sensitivity was 62.5%, and negative predictive value was 92.5%. In two patients there was no detection of sentinel nodes and in addition in two patients only sentinel nodes were harvested due to minimal disease. No side effects occurred.
Conclusions:
This new and simple approach yielded a high pelvic detection rate. This new approach reveals a way to label sentinel nodes in endometrial cancer. Combining a different labeling agent with the proposed new method might overcome the lack of para-aortic sentinel detection.
