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Published on: September 26, 2018
Blood pressure and control of cardiovascular risk
1John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia. director@jcsmr.anu.edu.au
Insights
Early cardiovascular disease risk assessment incorrectly focused on diastolic pressure and defined hypertension discretely. Current understanding emphasizes continuous blood pressure risk and comprehensive prevention strategies beyond just treating hypertension.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Historically, diastolic pressure was considered primary for cardiovascular risk, and hypertension was viewed as a distinct condition.
- These early 20th-century concepts have been revised with new scientific understanding.
Purpose of the Study:
- To highlight the shift in understanding cardiovascular disease risk factors.
- To emphasize the move from a dichotomous view of blood pressure to a continuous risk model.
- To advocate for comprehensive cardiovascular disease prevention strategies.
Main Methods:
- Review of historical and contemporary concepts in blood pressure management and cardiovascular risk.
- Analysis of the evolution of hypertension definitions and risk classification.
- Examination of the paradigm shift towards comprehensive cardiovascular disease prevention.
Main Results:
- Systolic pressure is now recognized as the primary risk factor for cardiovascular disease.
- Hypertension is understood as an arbitrary definition, with risk being continuous across blood pressure levels.
- A shift from single-factor to comprehensive risk prevention is evident.
Conclusions:
- Cardiovascular disease prevention requires lowering blood pressure and managing associated risk factors, not solely treating hypertension.
- The understanding of blood pressure as a continuous risk factor is crucial for effective prevention.
- The World Health Organization (WHO)-International Society of Hypertension (ISH) 2003 statement reflects this updated approach.
Abstract:
Two key early 20th century notions, the first the primacy of diastolic pressure in determining risk, and the second that hypertension is a discrete disorder, have proved to be incorrect. We now recognize the primacy of systolic pressure as a risk factor for cardiovascular disease and that hypertension is an arbitrary definition. In the early 21st century, we are moving away from a dichotomous approach to risk classification, and away from notions of hypertension and normotension towards an appreciation that blood pressure-related risk is continuous. In parallel, there has been a paradigm shift from a single risk factor approach to comprehensive cardiovascular disease risk prevention. Accordingly, prevention of cardiovascular disease requires a focus on lowering of blood pressure and modification of associated risk factors rather than simply treatment of hypertension. This emphasis is reflected in the World Health Organization (WHO)-International Society of Hypertension (ISH) 2003 statement on management of hypertension.
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