Related Experiment Video
Updated: Jul 16, 2026

08:51
Intraductal Injection of LPS as a Mouse Model of Mastitis: Signaling Visualized via an NF-κB Reporter Transgenic
Published on: September 4, 2012
Lupus mastitis is not a surgical disease
Sancar Bayar1, Ebru Dusunceli, Koray Ceyhan
1Department of Surgery, Section of Surgical Oncology, Ankara University School of Medicine, Ankara, Turkey. sancarb@hotmail.com
The Breast Journal
|February 27, 2007
Summary
Lupus mastitis, a rare breast condition in patients with systemic lupus erythematosus (SLE), can mimic breast cancer. Early diagnosis and medical management are key for successful treatment, often avoiding surgery.
Area of Science:
- Rheumatology
- Oncology
- Pathology
Background:
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
- Breast masses in SLE patients raise concerns for malignancy, necessitating a thorough differential diagnosis.
- Lupus mastitis is an uncommon but important differential diagnosis for breast lesions in SLE patients.
Observation:
- A 23-year-old woman with a history of discoid lupus presented with a palpable right upper quadrant breast mass.
- Physical examination revealed a 5 cm irregular, hard lesion, initially suspicious for malignancy.
- Ultrasound-guided fine needle aspiration biopsy was performed for diagnostic evaluation.
Findings:
- Histopathological analysis confirmed the breast mass as lupus mastitis.
- The findings underscore the importance of considering lupus mastitis in the differential diagnosis of breast masses in SLE patients.
- Lupus mastitis can present as a discrete mass mimicking breast cancer.
Implications:
- Prompt diagnosis of lupus mastitis can prevent unnecessary surgical intervention.
- Medical management is typically effective for lupus mastitis, leading to favorable outcomes.
- Increased awareness of lupus mastitis among clinicians is crucial for timely and appropriate patient care.
