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Related Experiment Videos

Autonomic peripheral neuropathy.

Roy Freeman1

  • 1Department of Neurology, Harvard Medical School, Center for Autonomic and Peripheral Nerve Disorders, Beth Israel Deaconess Medical Center, One Deaconess Road, Boston, MA 02215, USA. rfreeman@bidmc.harvard.edu

Neurologic Clinics
|February 28, 2007
PubMed
Summary
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Autonomic dysfunction is common in peripheral polyneuropathies, especially those targeting small nerve fibers. This condition significantly impacts cardiovascular, gastrointestinal, and other bodily functions.

Area of Science:

  • Neurology
  • Autonomic Nervous System Research

Background:

  • Generalized peripheral polyneuropathies frequently involve autonomic dysfunction.
  • A subset of these neuropathies selectively targets small or unmyelinated nerve fibers.

Purpose of the Study:

  • To highlight autonomic dysfunction as a primary manifestation in small fiber polyneuropathies.
  • To detail the specific autonomic functions affected.

Main Methods:

  • Clinical assessment of autonomic dysfunction.
  • Subclinical evaluation of autonomic function.

Main Results:

  • Autonomic dysfunction is a prominent feature in small fiber polyneuropathies.
  • Impairments observed in cardiovascular, gastrointestinal, urogenital, thermoregulatory, sudomotor, and pupillomotor functions.

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Conclusions:

  • Small fiber polyneuropathies are characterized by significant autonomic dysfunction.
  • Understanding these impairments is crucial for managing patients with autonomic neuropathy.