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Prophylactic oophorectomy: a historical perspective.

Ornella Moscucci1, Aileen Clarke

  • 1Centre for History in Public Health, Department of Health and Public Policy, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. ornella.moscucci@lshtm.ac.uk

Journal of Epidemiology and Community Health
|February 28, 2007
PubMed
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Bilateral oophorectomy, the removal of both ovaries, is common for cancer prevention. A comprehensive risk-benefit analysis is needed for this prophylactic surgery, especially when performed during hysterectomy without genetic markers.

Area of Science:

  • Reproductive medicine
  • Surgical oncology
  • Medical history

Background:

  • Bilateral oophorectomy is a surgical procedure involving the removal of both ovaries.
  • It is performed globally for various reasons, including cancer prevention and treatment.

Observation:

  • In 2003, approximately 19,000 women under 60 in the UK underwent prophylactic bilateral oophorectomy.
  • This procedure is often a preventative measure against ovarian and breast cancer, particularly in women with increased genetic risk.

Findings:

  • A comprehensive evaluation of the risks, costs, and benefits of prophylactic oophorectomy, especially when performed without genetic risk markers and concurrently with hysterectomy, is lacking.
  • Historical approaches to ovarian surgery in Britain since the 19th century reveal evolving perspectives on its advantages and disadvantages.

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Implications:

  • This historical review aims to illuminate the complexities surrounding ovarian removal.
  • Informing a more evidence-based assessment of current prophylactic oophorectomy practices is crucial for patient care and surgical decision-making.