Related Experiment Video
Updated: Jul 16, 2026

Synthetic Condensates and Cell-Like Architectures from Amphiphilic DNA Nanostructures
Published on: May 31, 2024
Synthetic metallomolecules as agents for the control of DNA structure
Adair D Richards1, Alison Rodger
1Molecular Organisation and Assembly in Cells Doctoral Training Centre, University of Warwick, Coventry, CV4 7AL, UK.
Abstract:
This tutorial review summarises B-DNA structure and metallomolecule binding modes and illustrates some DNA structures induced by molecules containing metallic cations. The effects of aquated metal ions, cobalt amines, ruthenium octahedral metal complexes, metallohelicates and platinum complexes such as cis-platin are discussed alongside the techniques of NMR, X-ray crystallography, gel electrophoresis, circular dichroism, linear dichroism and molecular dynamics. The review will be of interest to people interested in both DNA structure and roles of metallomolecules in biological systems.
Related Concept Videos
DNA Topoisomerases
Types and Mechanism of action
Topoisomerases are divided into two main types. Type I...
Inhibitors of Bacterial DNA Synthesis
Maxam-Gilbert Sequencing
Challenges of the Maxam-Gilbert Method
The...
Spontaneous and Induced Mutations
Single-Strand DNA Binding Proteins

