SgIGSF is a novel biliary-epithelial cell adhesion molecule mediating duct/ductule development

Akihiko Ito1, Yuji Nishikawa, Kazuhiro Ohnuma

  • 1Division of Surgical Pathology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan. akito@med.kobe-u.ac.jp

Hepatology (Baltimore, Md.)
|February 28, 2007
PubMed
Summary

Spermatogenic immunoglobulin superfamily (SgIGSF) functions as a biliary epithelial cell adhesion molecule during active bile duct formation in developing and regenerating livers. Its expression is transient and crucial for ductule development, as blocking it inhibits cell processes.

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