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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
Life expectancy after perimesencephalic subarachnoid hemorrhage
Paut Greebe1, Gabriël J E Rinkel
1Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre, Utrecht, The Netherlands.
Stroke
|March 3, 2007
Summary
Patients with perimesencephalic nonaneurysmal subarachnoid hemorrhage have a normal life expectancy and no increased risk of rebleeding. These findings suggest no restrictions should be placed on patients by insurance companies.
Area of Science:
- Neurology
- Neurosurgery
- Public Health
Background:
- Perimesencephalic nonaneurysmal subarachnoid hemorrhage (PNH) patients face uncertainty regarding long-term prognosis.
- These patients are often unfairly categorized as high-risk for insurance purposes.
- Previous studies lacked comprehensive long-term mortality data for PNH cohorts.
Purpose of the Study:
- To conduct a very long-term follow-up of a large PNH patient cohort.
- To compare the mortality rates of PNH patients with the general population.
- To address the long-term prognosis and insurance implications for PNH survivors.
Main Methods:
- A consecutive series of 160 PNH patients (1983-2005) were followed via telephone.
- Mortality data, including age and cause of death, were collected for deceased patients.
- Standardized mortality ratios (SMR) were calculated and compared to general population rates.
Main Results:
- The cohort comprised 160 patients with 1213 patient-years of follow-up.
- No recurrent subarachnoid hemorrhage events were reported.
- The observed mortality was lower than expected (SMR 0.61), indicating normal life expectancy.
Conclusions:
- Patients with perimesencephalic hemorrhage exhibit normal life expectancy.
- There is no increased risk of rebleeding or premature death in the long term.
- Physicians and insurance companies should not impose restrictions on PNH patients.
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