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Psychosurgery

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

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Related Experiment Video

Updated: Jul 16, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Surgery for temporal lobe epilepsy.

Warren Boling¹, Nicoletta Longoni, Adriana Palade

¹Dept. of Neurosurgery, West Virginia University School of Medicine, Morgantown, USA.

The West Virginia Medical Journal

|March 6, 2007

Summary

For drug-resistant epilepsy, epilepsy surgery offers a high chance of seizure control. This study found surgery significantly improved or eliminated seizures in 96% of patients with intractable temporal lobe epilepsy.

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Last Updated: Jul 16, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

Area of Science:

Neurology
Neurosurgery
Epilepsy Research

Background:

Intractable epilepsy causes significant disability, social stigma, and mortality.
Standard anticonvulsant treatments often fail for individuals with uncontrolled epilepsy.
Medical societies recommend comprehensive epilepsy programs for medically intractable cases.

Purpose of the Study:

To evaluate the efficacy of epilepsy surgery for intractable temporal lobe epilepsy.
To determine seizure control rates and functional outcomes following surgical intervention.

Main Methods:

A retrospective review of 48 patients undergoing surgery for intractable temporal lobe epilepsy.
Assessment of seizure freedom and significant improvement post-surgery.

Main Results:

35 (73%) patients achieved complete seizure freedom after surgery.
96% of patients experienced seizure freedom or significant improvement.
Epilepsy surgery demonstrated superior outcomes compared to medical management alone.

Conclusions:

Surgery for intractable temporal lobe epilepsy offers a high success rate.
Surgical intervention is a viable and effective treatment option for selected patients with refractory epilepsy.