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Updated: Jul 16, 2026
13:55
Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
Published on: January 27, 2019
[Donor-transmitted infections].
1Servicio Enfermedades Infecciosas, Hospital Vall d'Hebron, Barcelona, España. olen@ir.vhebron.net
Enfermedades Infecciosas Y Microbiologia Clinica
|March 6, 2007
Summary
Transplant recipients face infection risks from donor organs due to immunosuppression. This review assesses donor infection screening and the benefits versus risks of using organs from infected donors to improve transplant outcomes.
Area of Science:
- Transplantation immunology
- Infectious disease transmission
- Organ transplantation
Background:
- Solid organ transplant recipients have a weakened immune system due to immunosuppressive therapy.
- Infections transmitted via donor organs can lead to graft failure and patient mortality.
- Careful risk assessment is crucial for utilizing organs from infected donors.
Purpose of the Study:
- To review current knowledge on screening potential organ donors for infections.
- To discuss the risk-benefit analysis of using organs from infected donors.
- To optimize organ utilization while minimizing adverse transplant outcomes.
Main Methods:
- Literature review of current practices and research on donor infection screening.
- Analysis of risk factors and outcomes associated with using organs from infected donors.
- Discussion of strategies for managing infectious risks in transplantation.
Main Results:
- Immunosuppression significantly impairs the defense against infections in transplant recipients.
- Donor-derived infections pose a serious threat to allograft survival and recipient health.
- Effective screening protocols and risk-benefit evaluations are essential for safe organ transplantation.
Conclusions:
- Screening potential donors for infections is critical to prevent post-transplant complications.
- Judicious use of organs from infected donors, guided by thorough risk assessment, can be beneficial.
- Balancing organ availability with patient safety is paramount in organ transplantation.
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