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Updated: Jul 16, 2026
Quantitative Analyses of all Influenza Type A Viral Hemagglutinins and Neuraminidases using Universal Antibodies in Simple Slot Blot Assays
Published on: April 4, 2011
Hu and Yo antibodies have heterogeneous avidity
Cecilie Totland1, Jan Aarseth, Christian Vedeler
1Department of Neurology, Haukeland University Hospital, Norway; Department of Clinical Medicine, University of Bergen, Norway.
Abstract:
Onconeural antibodies such as anti-Hu and anti-Yo may be important in the pathogenesis of paraneoplastic neurological syndromes. The avidity of these antibodies is not known. In this study, we compared the avidity of Hu and Yo antibodies both at single time points and over a time range of 2 months to 6 years. The avidity of Yo and Hu antibodies differed among the patients, but anti-Yo generally had higher avidity than anti-Hu. Whether Yo antibodies are more pathogenic than Hu antibodies are presently unknown.
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