Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aggrecan: Approaches to Study Biophysical and Biomechanical Properties.

Methods in molecular biology (Clifton, N.J.)·2021
Same author

Trypsin Pre-Treatment Combined With Growth Factor Functionalized Self-Assembling Peptide Hydrogel Improves Cartilage Repair in Rabbit Model.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2019
Same author

The Effects of Waveform and Current Direction on the Efficacy and Test-Retest Reliability of Transcranial Magnetic Stimulation.

Neuroscience·2018
Same author

Relation of Anterior Cruciate Ligament Tears to Potential Chronic Cardiovascular diseases.

The American journal of cardiology·2018
Same author

Reduced motor cortex inhibition and a 'cognitive-first' prioritisation strategy for older adults during dual-tasking.

Experimental gerontology·2018
Same author

The Illusion of the Perfect Brain Enhancer.

Cerebrum : the Dana forum on brain science·2018
Same journal

Investigating the Neural Origins of Ear-EEG: A Correlation Study Using Scalp EEG Source Reconstruction.

NeuroImage·2026
Same journal

Hysteresis effects in visual and auditory perception and the comparison of underlying neural mechanisms - an EEG study.

NeuroImage·2026
Same journal

Short-term audio-tactile training affects cortical auditory speech-envelope tracking for incongruent but not congruent stimuli.

NeuroImage·2026
Same journal

Dissociable Neurocognitive Mechanisms of State and Trait Anxiety in Working Memory: Threat-Induced Alterations in Decision Dynamics and Attenuation of Large-Scale Network Reconfiguration.

NeuroImage·2026
Same journal

Neuro-Ocular Amyloid Characterization in Alzheimer's Disease via Cross-Site PET-MRI and Hierarchical Cross-Attention Driven Multimodal Representation Learning.

NeuroImage·2026
Same journal

Whole-brain network dynamics underlying intolerance of uncertainty.

NeuroImage·2026
See all related articles

Related Experiment Video

Updated: Jun 28, 2026

Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
13:35

Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging

Published on: April 27, 2014

Transcranial direct current stimulation: a computer-based human model study.

Tim Wagner1, Felipe Fregni, Shirley Fecteau

  • 1Center for Non-invasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA. twagner@mit.edu <twagner@mit.edu>

Neuroimage
|March 6, 2007
PubMed
Summary
This summary is machine-generated.

This study models transcranial direct current stimulation (tDCS) using MRI data. Findings show brain lesions can alter tDCS current flow, potentially guiding optimized treatments for patients.

More Related Videos

Stimulation Location Determination using a 3D Digitizer with High-Definition Transcranial Direct Current Stimulation
07:20

Stimulation Location Determination using a 3D Digitizer with High-Definition Transcranial Direct Current Stimulation

Published on: December 20, 2019

High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity
06:11

High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity

Published on: September 26, 2025

Related Experiment Videos

Last Updated: Jun 28, 2026

Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
13:35

Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging

Published on: April 27, 2014

Stimulation Location Determination using a 3D Digitizer with High-Definition Transcranial Direct Current Stimulation
07:20

Stimulation Location Determination using a 3D Digitizer with High-Definition Transcranial Direct Current Stimulation

Published on: December 20, 2019

High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity
06:11

High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity

Published on: September 26, 2025

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Computational Modeling

Background:

  • Transcranial direct current stimulation (tDCS) shows growing clinical interest, but its efficacy and mechanisms require further understanding.
  • Accurate modeling is crucial for optimizing tDCS protocols and predicting outcomes.

Purpose of the Study:

  • To develop a realistic, MRI-derived finite element model for simulating electric currents in the human brain during tDCS.
  • To analyze current density distributions in healthy and pathologically altered brain models.

Main Methods:

  • Utilized magnetic resonance imaging (MRI) data to create a finite element model of the human head.
  • Simulated current density distributions for various electrode montages in healthy and cortical infarct models.

Main Results:

  • Calculated cortical current density magnitudes ranging from 0.77 to 2.00 mA/cm(2) for 1 mA tDCS.
  • Demonstrated that cortical strokes can increase and relocate current density maxima compared to healthy brain models.

Conclusions:

  • The developed model provides insights into tDCS current flow in both healthy individuals and patients with focal brain lesions.
  • Results can inform the optimization of tDCS parameters for therapeutic applications in diverse patient populations.