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Updated: Jul 16, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Secondary exposure for 73 and 200 MeV proton therapy
F Trompier1, S Delacroix, I Vabre
1Institut de Radioprotection et de Sûreté Nucléaire (IRSN), BP 17, F-92262 Fontenay-aux-Roses Cedex, France. francois.trompier@irsn.fr
Abstract:
Following modifications on the beam line at the Orsay Protontherapy Center, dose measurements were performed in order to make a dose map in the treatment rooms and in the delimited radiation-controlled area around beam line. Measurements were performed using tissue-equivalent proportional counters and rem-counters. Analysis of TEPC single event measurements showed that high LET components (>10 keV.microm(-1)) represent 90 to 99% of total dose equivalent in the treatment rooms and 50 to 90% in the controlled area and quality factors range, respectively between 2 and 15. A fast neutron component was identified in the treatment rooms, where dose equivalent rate varied between few microSv.h(-1) to some dozen of mSv.h(-1). In high-energy radiation field rem-counters underestimated TEPC values for neutron component. The variation between instruments response according to the location is linked to energetic spectrum variations and instrument characteristics.
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