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Updated: Jul 16, 2026

Speciation and Bioavailability Measurements of Environmental Plutonium Using Diffusion in Thin Films
Published on: November 9, 2015
Worldwide bioassay data resources for plutonium/americium internal dosimetry studies
G Miller1, A E Riddell, R Filipy
1Los Alamos National Laboratory, HSR-12, Los Alamos, NM, USA. guthrie@lanl.gov
Biokinetic models require human bioassay data for validation. This study reviews three major plutonium/americium databases and proposes a uniform XML standard for improved data consistency in internal dosimetry.
Area of Science:
- Radiological protection
- Internal dosimetry
- Biokinetics
Background:
- Biokinetic models are essential for internal dosimetry.
- Model validation relies on human bioassay data.
- Existing bioassay databases lack standardization.
Purpose of the Study:
- To describe key human bioassay databases for plutonium and americium.
- To advocate for a standardized database format.
- To explore the suitability of XML for this standard.
Main Methods:
- Review of three major plutonium/americium bioassay databases: Sellafield, Los Alamos, and the United States Transuranium Registry.
- Discussion of data standardization requirements.
- Evaluation of the eXtensible Markup Language (XML) as a potential standard format.
Main Results:
- Identification and description of three significant human bioassay databases.
- Highlighting the need for a uniform data format across these databases.
- Proposal of XML as a suitable standard for structuring bioassay data.
Conclusions:
- Standardized bioassay data formats are crucial for validating biokinetic models.
- A uniform database structure, potentially using XML, will enhance the reliability of internal dosimetry.
- Inter-database comparisons and model development will benefit from standardized data.
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