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Primary hyperparathyroidism: King Khalid University Hospital Experience.
1Department of Medicine, King Khalid University Hospital, Riyadh, Saudi Arabia.
Annals of Saudi Medicine
|March 6, 2007
Summary
Primary hyperparathyroidism is not rare in Saudi Arabia, often presenting late with complications. Early screening for calcium is recommended to reduce morbidity from this treatable disorder.
Area of Science:
- Endocrinology
- Bone Metabolism
- Nephrology
Background:
- Primary hyperparathyroidism (PHP) prevalence, presentation, and management were studied in Saudi Arabia.
- A retrospective analysis of 24 PHP cases at King Khalid University Hospital (1982-1997) was conducted.
Purpose of the Study:
- To determine the prevalence of PHP in Saudi Arabia.
- To describe the clinical presentation, diagnostic methods, and treatment outcomes for PHP.
Main Methods:
- Retrospective analysis of 24 primary hyperparathyroidism cases.
- Review of patient demographics, clinical symptoms, biochemical data, imaging results, and surgical outcomes.
Main Results:
- Prevalence estimated at 11.34 per 100,000 population; 92% presented with hypercalcemia.
- Musculoskeletal and renal complications were common (62-67% and 58%, respectively).
- Thallium-technetium subtraction scans (83% sensitivity) and CT scans (86% sensitivity) were effective diagnostic tools; 87.5% underwent successful surgery for parathyroid adenoma.
Conclusions:
- PHP is not rare in Saudi Arabia and tends to present late with complications.
- Routine calcium screening and early identification are crucial for reducing morbidity.
- PHP is an easily treatable disorder with significant potential for morbidity if not managed promptly.
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