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Updated: Jul 16, 2026

Isolating and Analyzing Cells of the Pancreas Mesenchyme by Flow Cytometry
Published on: January 28, 2017
[Ultrastructure of endocrine cells in the dog pancreas]
Abstract:
Electron microscopy was used to study the cellular composition of dog pancreatic islets. Four types of endocrine cells were detected: A, B, D and PP. B cells were the predominant population within the islets. Differences in cellular organization of A and B cells were shown to be caused by the phases of the process of hormone synthesis. Insulin-containing secretory granules in B cells had a crystalloid structure, similar to that in B granules of insulin-containing cells in human pancreatic islets. In the exocrine portion of the pancreas, acino-insular cells were detected that simultaneously contained B granules and zymogen granules in their cytoplasm. It is suggested, that their presence is indicative of one of possible directions of pancreatic islet regeneration.
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