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Updated: Jul 16, 2026

Adult Mouse Digit Amputation and Regeneration: A Simple Model to Investigate Mammalian Blastema Formation and Intramembranous Ossification
Published on: July 12, 2019
[Stem cells and reparative regeneration in mammalian postnatal ontogenesis]
Abstract:
This paper presents the critical analysis of the data published in recent literature, which concern the role and significance of stem cells (embryonic stem cells and progenitor cells) in the processes of reparative morpho- and histogenesis in the different animal and human organs. Possible negative effects of the application of stem cells for the stimulation of reparative histo- and organogenesis are discussed. Special attention is drawn to the necessity of more cautious and balanced approach to the use of stem cells for stimulation of repair processes in the organism.
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