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[Epidemiological survey of pneumococcus serotypes in pediatric patients with acute suppurative otitis media]

Hitoshi Kamiya1, Tatsuo Kato, Takehiro Togashi

  • 1National Hospital Organization Mie Hospital.

Kansenshogaku Zasshi. the Journal of the Japanese Association for Infectious Diseases
|March 7, 2007
PubMed

Insights

The most common Streptococcus pneumoniae serotypes in young children with otitis media were 19F, 6B, and 23F. The 7-valent pneumococcal conjugate vaccine covered 62.7% of isolates, with higher coverage for resistant strains.

Area of Science:

  • Pediatrics
  • Microbiology
  • Vaccinology

Context:

  • Acute suppurative otitis media (ASOM) is a common childhood infection.
  • Streptococcus pneumoniae is a leading cause of ASOM.
  • Antibiotic resistance in Streptococcus pneumoniae is a growing public health concern.

Purpose:

  • To identify Streptococcus pneumoniae serotypes causing ASOM in children under six.
  • To assess the serotype coverage of the 7-valent pneumococcal conjugate vaccine (PCV7).
  • To analyze trends in penicillin-resistant Streptococcus pneumoniae (PRSP).

Summary:

  • A prospective study analyzed 201 Streptococcus pneumoniae isolates from children with ASOM in Japan.
  • Serotype 19F was most prevalent (25.9%), followed by 6B (14.9%) and 23F (11.9%).
  • PCV7 coverage was 62.7%, with 59.7% of isolates showing penicillin resistance (PISP and PRSP).

Impact:

  • Findings highlight the importance of serotype surveillance for vaccine efficacy.
  • High rates of penicillin resistance underscore the need for ongoing monitoring and treatment strategies.
  • PCV7 demonstrated significant, though incomplete, coverage against resistant strains.

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