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Ultrafast computed tomography in experimental pulmonary embolism.
J J Geraghty1, W Stanford, S K Landas
1Department of Radiology, University of Iowa College of Medicine, Iowa City 52242.
Investigative Radiology
|January 1, 1992
Summary
Ultrafast CT (UFCT) reliably detects experimental peripheral pulmonary emboli in dogs. This imaging technique accurately identified all Gelfoam emboli, showing promise for diagnosing peripheral lung clots.
Area of Science:
- Radiology
- Pulmonary Medicine
- Medical Imaging
Background:
- Computed tomography (CT) is valuable for central pulmonary embolism diagnosis.
- The efficacy of CT in detecting peripheral pulmonary emboli remains unestablished.
Purpose of the Study:
- To evaluate the diagnostic utility of ultrafast CT (UFCT) for identifying experimental peripheral pulmonary emboli.
Main Methods:
- Seven dogs underwent pulmonary artery embolization with Gelfoam.
- Contiguous 3-mm axial UFCT scans were acquired post-contrast administration.
- Emboli locations were compared between UFCT imaging and autopsy findings.
Main Results:
- All 21 Gelfoam emboli were successfully identified on UFCT images.
- UFCT findings precisely correlated with autopsy-determined emboli locations.
- UFCT demonstrated reliable detection of emboli in second- to fourth-division pulmonary vessels.
Conclusions:
- Ultrafast CT is a reliable method for detecting peripheral pulmonary emboli in experimental models.
- Further research is required to ascertain UFCT's effectiveness in visualizing in vivo blood clots.