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Related Concept Videos

Embryonic Stem Cells00:57

Embryonic Stem Cells

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
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Stem Cell Culture01:17

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Stem Cell Therapy for Tissue Regeneration01:21

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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iPS Cell Differentiation01:22

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The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
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Induced Pluripotent Stem Cells01:06

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Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
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Adult Stem Cells01:33

Adult Stem Cells

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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Stem cell research in China.

Lianming Liao1, Lingsong Li, Robert Chunhua Zhao

  • 1Centre of Excellence in Tissue Engineering, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Dongdan Santiao No. 5, Beijing 100005, People's Republic of China.

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|March 8, 2007
PubMed
Summary

China is advancing stem cell research, focusing on bone marrow and embryonic stem cells. Clinical trials show promise for treating heart failure, liver failure, and ischemia, supported by favorable ethical guidelines.

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Area of Science:

  • Biomedical research
  • Regenerative medicine

Background:

  • China has significantly boosted stem cell research and clinical applications in the last five years.
  • Focus areas include bone marrow and embryonic stem cells for basic research.

Purpose of the Study:

  • To review the advancements in stem cell research and practice in China.
  • To highlight clinical applications and ethical frameworks governing stem cell research.

Main Methods:

  • Review of recent developments in Chinese stem cell research.
  • Analysis of reported clinical applications and ethical guidelines.

Main Results:

  • Successful clinical applications reported for acute heart failure, acute liver failure, and lower limb ischemia.
  • China established 'Ethical Guidelines for Human Embryonic Stem Cell Research' in 2003.
  • The country offers a liberal and favorable environment for human embryonic stem cell research.

Conclusions:

  • China is a leading environment for stem cell research, with growing clinical applications.
  • Ethical guidelines support the advancement of human embryonic stem cell research in China.