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Updated: Jul 16, 2026
10:16
Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging
Published on: February 10, 2012
[Contrast media and percutaneous coronary interventions].
P Aubry1, X Halna du Fretay, D Tchetche
1Departement de cardiologie, centre hospitalier Bichat-Claude Bernard, 46, Rue Henri-Huchard, 75018 Paris, France. pcaubry@yahoo.fr
Annales De Cardiologie Et D'Angeiologie
|March 9, 2007
Summary
This review examines risks associated with contrast media used in percutaneous coronary interventions, highlighting knowledge gaps and the need for further research on adverse effects.
Area of Science:
- Cardiology
- Radiology
- Pharmacology
Context:
- Percutaneous coronary interventions (PCI) frequently utilize contrast media.
- France offers approximately a dozen types of contrast media.
- Low-osmolar and iso-osmolar contrast media are preferred due to safety profiles.
Purpose:
- To review contrast media-related risks in PCI.
- To elucidate underlying mechanisms of adverse effects.
- To discuss prophylaxis strategies and inter-agent differences.
Summary:
- Key risks include hypersensitivity, arrhythmias, and contrast-induced nephrotoxicity.
- Effects on coagulation and platelets are also considered.
- Current recommendations for appropriate use are insufficient, with persistent uncertainties.
Impact:
- Provides a comprehensive overview of contrast media risks in PCI.
- Identifies areas requiring further investigation through randomized trials.
- Aims to improve the safe and effective use of contrast media in clinical practice.
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