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05:56
Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
Published on: August 29, 2025
Transient recurrent ascites
Nsinire L Kahegeshe1, Anne Pestiaux, Jean-Paul Henry
1Department of Gastroenterology and Hepaticopancreatology, Erasme Hospital, University Clinics of Brussels, Free University of Brussels, Brussels, Belgium. nkahegeshe@hotmail.com
Acta Gastro-Enterologica Belgica
|March 9, 2007
Summary
Angiotensin-converting enzyme (ACE) inhibitors can cause rare but serious side effects. This case highlights a delayed diagnosis of ACE inhibitor-induced angioedema affecting the small bowel, emphasizing the need for vigilance.
Area of Science:
- Cardiology
- Gastroenterology
- Pharmacology
Background:
- Angiotensin-converting enzyme (ACE) inhibitors are mainstays in cardiovascular disease management.
- Fosinopril is a commonly prescribed ACE inhibitor.
Observation:
- A young woman developed recurrent gastrointestinal symptoms including abdominal pain, vomiting, and diarrhea.
- Physical examination revealed peritoneal signs, and imaging showed ascites and ileitis.
- The patient underwent surgery due to the severity of symptoms.
Findings:
- A diagnosis of ACE inhibitor-induced angioedema of the small bowel was established after the fourth symptomatic episode.
- Discontinuation of fosinopril led to complete resolution of symptoms.
Implications:
- This case underscores the potential for delayed-onset, severe gastrointestinal complications from ACE inhibitors.
- Accurate diagnosis requires high clinical suspicion, especially with recurrent abdominal symptoms.
- Awareness of this adverse effect is crucial for clinicians managing patients on ACE inhibitors.
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