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Updated: Jul 16, 2026

09:49
Fast Enzymatic Processing of Proteins for MS Detection with a Flow-through Microreactor
Published on: April 6, 2016
A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release
Ian R Baxendale1, Steven V Ley, Christopher D Smith
1Innovative Technology Centre, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW.
Abstract:
A general flow process for the multi-step assembly of peptides has been developed and this procedure has been used to successfully construct a series of Boc, Cbz and Fmoc N-protected dipeptides in excellent yields and purities, including an extension of the method to enable the preparation of a tripeptide derivative.

