Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Variations in thyroid function and sleep in healthy young men.

M W Johns, J P Masteron, J E Paddle-Ledinek

    Clinical Science and Molecular Medicine
    |December 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Assessment of F-RNA coliphage as a potential indicator of enteric virus contamination of hog carcasses.

    Journal of food protection·2012
    Same author

    Ascorbic acid in the milk of Melbourne women.

    The Medical journal of Australia·2010
    Same author

    The effect of pre-treatment and sonication of centrifugal ultrafiltration devices on virus recovery.

    Journal of virological methods·2009
    Same author

    Changes in the proteome of Escherichia coli during growth at 15 degrees C after incubation at 2, 6 or 8 degrees C for 4 days.

    International journal of food microbiology·2008
    Same author

    Somatostatin receptors.

    Trends in endocrinology and metabolism: TEM·2008
    Same author

    Prosomatostatin is proteolytically processed at the amino terminal segment by subtilase SKI-1.

    Regulatory peptides·2004

    Thyroid function in healthy men shows minimal daily changes in free thyroxine index (FTI). However, day-to-day FTI variations correlate with sleep patterns, suggesting physiological significance.

    Area of Science:

    • Endocrinology
    • Sleep Medicine
    • Human Physiology

    Background:

    • Thyroid hormones regulate metabolism and physiological processes.
    • Understanding diurnal and day-to-day variations in thyroid function is crucial for interpreting clinical results.

    Purpose of the Study:

    • To investigate diurnal and day-to-day variations in thyroid function parameters in healthy young men.
    • To explore the relationship between thyroid function variations and sleep patterns.

    Main Methods:

    • Repeated measurements of total serum thyroxine, tri-iodothyronine resin uptake, total plasma protein, and free thyroxine index (FTI) over four days.
    • Assessment of sleep patterns using electroencephalogram (EEG).

    Main Results:

    Related Experiment Videos

  • Total serum thyroxine showed diurnal variation, but FTI remained relatively stable throughout the day.
  • Significant day-to-day FTI variations were observed in some subjects, independent of protein binding capacity.
  • Higher FTI levels correlated with fragmented sleep, reduced REM sleep, and increased delta-wave sleep.

    • Conclusions:

    • Free thyroxine levels exhibit minimal diurnal variation in healthy men.
    • Day-to-day fluctuations in thyroid function may have physiological significance and impact sleep architecture.
    • The underlying causes for these day-to-day thyroid function variations require further investigation.