Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 16, 2026

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release
06:02

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release

Published on: June 12, 2021

Microbubble ultrasound contrast agents: an update.

Emilio Quaia1

  • 1Department of Radiology, Cattinara Hospital, University of Trieste (Italy), Strada di Fiume 447, Trieste 34149, Italy,.quaia@units.it

European Radiology
|March 14, 2007
PubMed
Summary

Contrast-enhanced ultrasound (CEUS) uses advanced microbubble contrast agents for improved imaging. This technique enhances visualization of blood flow and organ perfusion, with applications in liver, spleen, and kidney imaging.

Related Concept Videos

Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AI-Based Scientific Manuscript Peer Review: Is It Ready for Adoption?

Tomography (Ann Arbor, Mich.)·2026
Same author

Myocardial T2 Star (T2*) in a Large Healthy Population: Correction Factors for a Segmental Approach Using Commercially Available Software in the Current MRI Era.

Tomography (Ann Arbor, Mich.)·2026
Same author

Cardiac magnetic resonance in Pompe disease: a systematic literature review.

La Radiologia medica·2026
Same author

Artificial Intelligence CT Texture Radiomics for Outcome Prediction After EVAR: A Narrative Review.

Diagnostics (Basel, Switzerland)·2026
Same author

How to Deal with Paper Rejection.

Tomography (Ann Arbor, Mich.)·2026
Same author

Eye Lens Radiation Exposure During TAVI: Current Evidence and Imaging-Based Strategies for Dose Reduction.

Tomography (Ann Arbor, Mich.)·2026

Area of Science:

  • Medical Imaging
  • Ultrasound Technology
  • Biomedical Engineering

Background:

  • Microbubble contrast agents have gained significant interest for ultrasound (US) imaging.
  • Contrast-enhanced US (CEUS) has evolved beyond Doppler US, offering improved contrast resolution and tissue signal suppression.
  • Microbubbles exhibit a safe profile, enhanced stability in circulation, and enable real-time scanning with prolonged organ insonation.

Purpose of the Study:

  • To review the expanding applications of CEUS in clinical practice.
  • To highlight the benefits of microbubble contrast agents in various imaging scenarios.
  • To discuss the role of CEUS in assessing organ perfusion and characterizing lesions.

Main Methods:

  • Utilizing specialized contrast-specific US techniques with low transmit power.
  • Employing microbubble contrast agents for enhanced signal detection and tissue differentiation.
  • Quantitative analysis of echo-signal intensity for organ perfusion assessment.

Main Results:

  • CEUS demonstrates effectiveness in liver, spleen, and kidney applications, including lesion characterization and perfusion quantification.
  • The technique allows assessment of macrovasculature and microvasculature in different parenchymas.
  • Applications extend to trauma assessment, vesico-ureteral reflux in children, and imaging of specific biologic processes with targeted microbubbles.

Conclusions:

  • CEUS is a valuable tool for enhancing diagnostic capabilities in various clinical settings.
  • Microbubble contrast agents significantly improve ultrasound imaging of organ perfusion and pathology.
  • The versatility of CEUS supports its expanding role in medical diagnostics and research.

Related Experiment Videos

Last Updated: Jul 16, 2026

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release
06:02

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release

Published on: June 12, 2021