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Updated: Jul 5, 2026
Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Osteogenic sarcoma in frontal sinus: one case with literature review]
Xiaomeng Zhang1, Chengzhang Yang, Weijia Kong
1Department of Otolaryngology, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. zhangxiaomeng@sohu.com
Objective:
To study the etiology, clinical manifestation, radiograph manifestation and treatment of osteogenic sarcoma in frontal sinus.
Method:
A case of osteogenic sarcoma of the frontal sinus is reported. Recurrent epistaxis and supra-orbital pain were presented as the chief complaint. CT scan revealed a mass in right frontal sinus and invasion to the inferior wall of the sinus. Treatment comprised lateral rhinotomy followed by radiotherapy and chemotherapy.
Result:
The patient was followed up 1 year and 9 month, and no recurrence or metastasis was found.
Conclusion:
The diagnosis of osteogenic sarcoma in frontal sinus should be made upon the following aspects: CT scan of the sinus, nasal endoscopic detection and biopsy. Radical surgery followed by radiotherapy and chemotherapy may be the main treatment.
