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Prevalence and risk factors for combined coronary artery disease and aortic aneurysm

Carlos Romério Costa Ferro1, Dinaldo Cavalcanti de Oliveira, Fábio de Freitas Guimarães Guerra

  • 1Hospital do Coração, Associação do Sanatório Sírio, São Paulo, SP, Brazil.

Arquivos Brasileiros De Cardiologia
|March 17, 2007
PubMed

Insights

Coronary artery disease (CAD) is highly prevalent in patients with aortic aneurysm (AA), especially abdominal aortic aneurysms (AAA). Early CAD screening is recommended for AA patients, particularly those with AAA.

Area of Science:

  • Cardiology
  • Vascular Surgery
  • Diagnostic Imaging

Background:

  • Coronary artery disease (CAD) is a significant comorbidity in patients with aortic aneurysm (AA).
  • Understanding the prevalence and risk factors of CAD in relation to different aortic aneurysm topographies is crucial for patient management.

Purpose of the Study:

  • To determine the prevalence of CAD in patients with AA.
  • To investigate differences in CAD prevalence and risk factors based on AA topography (thoracic, thoracoabdominal, abdominal).
  • To identify primary risk factors associated with CAD in AA patients.

Main Methods:

  • Prospective, nonrandomized study of 95 asymptomatic patients undergoing aortic CT and coronary angiography.
  • Patients classified into three groups based on AA topography: thoracic aortic aneurysm (TAA), thoracoabdominal aortic aneurysm (TAAA), and abdominal aortic aneurysm (AAA).
  • Statistical analysis included t-tests, ANOVA, and chi-square tests to compare CAD prevalence and risk factors across groups.

Main Results:

  • Overall CAD prevalence was 63.1%.
  • AAA group showed higher CAD prevalence (76%) compared to TAA (70%) and TAAA (30%).
  • Smoking and dyslipidemia were significantly more prevalent in AAA patients.

Conclusions:

  • Asymptomatic CAD is highly prevalent in patients with AA, with a notable concentration in those with AAA.
  • These findings underscore the necessity for diagnostic CAD stratification in AA patients, particularly those with AAA.
Abstract

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