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Antifungal agent and other constituents from Cynanchum otophyllum
Yi-Bin Zhao1, Yue-Mao Shen, Hong-Ping He
1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany. The Chinese Academy of Sciences, Kunming, Yunnan 650204, People' s Republic of China.
Abstract:
Seven constituents were isolated from the ethyl acetate extract of the rhizome of Cynanchum otophyllum Schneid (Asclepiadaceae). Their structures were determined as 1-(4-methoxy-3-(6-methoxy-3-acetylphenylperoxy)phenyl)ethanone (1), 1-(3-hydroxy-7-acetylnaphthalen-2-yl)ethanone (2), 1-(3,4-dihydroxyphenyl)ethanone (3), 1-(2,4-dihydroxyphenyl)ethanone (4), 1-(3-(3,6-dihydroxy-2-methylbenzoyl)-2,4-dihydroxyphenyl)ethanone (beishouwubenzophenone) (5), N,N-dimethylethanamine (6), and 2-oxo-2-phenylacetic acid (7), respectively, by spectral methods. Among them, 1 and 2 were new compounds; 1 had antifungal activity.
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