Related Experiment Video
Updated: Jul 16, 2026

A Structured Approach to Extubation in Mechanically Ventilated Rats
Published on: July 18, 2025
Weaning from mechanical ventilation
Nizar Eskandar1, Michael J Apostolakos
1University of Rochester, Strong Memorial Hospital, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Abstract:
Approximately 20% of all mechanically ventilated patients fail their first attempt to wean. Prolonged mechanical ventilation increases morbidity, mortality, and costs. No single weaning parameter predicts patient ability to wean. Weaning studies suggest that daily trials of spontaneous breathing for appropriate patients assured by standing protocol and driven by respiratory care practitioners and/or nurses improve the weaning process and patient outcome.
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