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Paterson-Brown Kelly syndrome
1Division of Radiology, College of Medicine, King Saud University-Abha Branch, Abha, Saudi Arabia.
Annals of Saudi Medicine
|March 1, 1996
Summary
Cervical esophageal webs, causing dysphagia in Paterson-Brown Kelly syndrome, often present with iron-deficiency anemia. Treatment with iron therapy and dilatation effectively resolved dysphagia in most patients.
Area of Science:
- Gastroenterology
- Otolaryngology
- Hematology
Background:
- Paterson-Brown Kelly syndrome, characterized by dysphagia, is often associated with cervical esophageal webs.
- Iron-deficiency anemia is a common comorbidity.
Purpose of the Study:
- To describe the clinical characteristics, management, and outcomes of patients with dysphagia due to cervical esophageal webs.
Main Methods:
- Retrospective review of eight patients diagnosed with cervical esophageal webs between 1987 and 1992.
- Evaluation of patient demographics, web characteristics, associated conditions, and treatment responses.
Main Results:
- Seven females and one male, predominantly middle-aged Arabs, were identified.
- All patients presented with iron-deficiency anemia; three had koilonychia.
- Dysphagia resolved significantly or completely in seven patients following iron therapy, pharyngoscopy/esophagoscopy, and dilatation.
- One patient developed postcricoid carcinoma, a known complication.
Conclusions:
- Cervical esophageal webs in Paterson-Brown Kelly syndrome are treatable, with iron therapy and endoscopic dilatation yielding positive outcomes.
- Early diagnosis and management are crucial to prevent complications such as malignancy.
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