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Updated: Jul 16, 2026
10:44
One-step Negative Chromatographic Purification of Helicobacter pylori Neutrophil-activating Protein Overexpressed in Escherichia coli in Batch Mode
Published on: June 18, 2016
[Helicobacter pylori and headache: a minireview]
R Pellicano1, L Savi, P De Martino
1S.C.D.U. Gastro-Epatologia, Azienda Ospedaliera San Giovanni Battista, Molinette, Torino, Italy. reynaldo_pellican@hotmail.com
Minerva Medica
|March 21, 2007
Summary
Helicobacter pylori (H. pylori) infection may be linked to headaches, with eradication relieving symptoms in some patients. However, the exact role of H. pylori in headache pathogenesis remains unclear, requiring further research.
Area of Science:
- Gastroenterology
- Neurology
- Infectious Diseases
Background:
- Helicobacter pylori (H. pylori) is linked to gastroduodenal diseases and extragastric conditions.
- The bacterium's role in headache pathogenesis is under investigation.
Purpose of the Study:
- To review the literature on the potential correlation between H. pylori infection and headaches.
- To examine epidemiological data, intervention trials, and pathogenetic mechanisms.
Main Methods:
- Literature review and analysis of existing studies.
- Examination of epidemiological prevalence, intervention trial outcomes, and pathogenetic theories.
- Focus on H. pylori eradication and its effect on headache symptoms.
Main Results:
- Epidemiological studies show no significant difference in H. pylori prevalence between headache patients and controls, except in specific subgroups.
- Bacterial eradication led to symptom disappearance in 23-28% of patients and reduced intensity, frequency, and duration in others.
- H. pylori's role in headache pathogenesis does not appear to involve oxidative stress.
Conclusions:
- The association between H. pylori infection and headache pathogenesis is currently unclear.
- Further research should focus on specific patient subgroups and the long-term benefits of H. pylori eradication.
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