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Published on: August 1, 2019
Exercise and colon cancer: primary and secondary prevention
Thomas H Trojian1, Ketan Mody, Philippe Chain
1University of Connecticut Health Center/Saint Francis Hospital and Medical Center, Department of Family Medicine, Hartford, CT 06105, USA. ttrojian@stfranciscare.org
Abstract:
Many studies have demonstrated the effects of exercise on both primary and secondary prevention of colon cancer. Exercise appears to have a dose-response reduction in the rate of colon cancer. The mechanism by which exercise provides this benefit is not known, but increase in insulin-like growth factor-binding protein and reduction of prostaglandins appear to be the likely cause. Once a person develops colon cancer the benefits of exercise appear to continue both by increasing quality of life and reducing cancer-specific and overall mortality.
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