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Published on: February 16, 2011
Introduction: Medicare Section 1013 and AHRQ's Effective Health Care Program
Schumarry H Chao1, Frank L Urbano
1SHC & Associates, Santa Monica, CA 90402, USA. schumarryc@verizon.net
The Agency for Healthcare Research and Quality (AHRQ) Effective Health Care Program studies pharmaceutical safety and effectiveness. This research provides crucial comparative data for high-cost treatments, including rheumatoid arthritis therapies.
Area of Science:
- Health Services Research
- Pharmacoeconomics
- Evidence-Based Medicine
Background:
- Section 1013 of the Medicare Prescription Drug, Improvement, and Modernization Act (MMA) of 2003 mandates healthcare outcomes research.
- The Agency for Healthcare Research and Quality (AHRQ) established the Effective Health Care Program to address data gaps in pharmaceutical safety and effectiveness.
- Studies focus on highly utilized and/or high-cost treatments where comparative data is lacking.
Purpose of the Study:
- To introduce Section 1013 of the MMA and the AHRQ Effective Health Care Program.
- To outline the program's objective: determining the safety and comparative effectiveness of pharmaceuticals.
- To highlight the role of AHRQ's Evidence-based Practice Centers (EPCs) and the Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Network.
Main Methods:
- Conducting health care outcomes studies through EPCs and the DEcIDE Network.
- Focusing on comparative effectiveness research for pharmaceuticals.
- Performing systematic reviews and meta-analyses on specific drug classes and conditions.
Main Results:
- Initiated reviews on treatments for rheumatoid arthritis, including nonbiologic disease-modifying antirheumatic drugs (DMARDs) and biologic anti-tumor necrosis factor (TNF)-alpha therapies.
- Identified key pharmaceutical topics for safety and comparative effectiveness evaluation.
- Established a framework for evidence generation and dissemination.
Conclusions:
- AHRQ's EPCs and DEcIDE Network are actively researching the safety and comparative effectiveness of various pharmaceuticals.
- Specific focus includes biologic and nonbiologic DMARDs, such as TNF antagonists.
- Final reports will be translated into accessible language and disseminated to all stakeholders for informed decision-making.
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