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Updated: Jul 16, 2026

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
Published on: July 26, 2022
Management of neuropathic orofacial pain
Michael A O Lewis1, Vidya Sankar, Antoon De Laat
1Oral Surgery, Medicine and Pathology, Dental School, Cardiff University, Cardiff, UK. lewismao@Cardiff.ac.uk <lewismao@Cardiff.ac.uk>
Abstract:
Current management of painful trigeminal neuropathies relies on pharmacological (topical and systemic), surgical, and complementary modalities. There is, however, a lack of quality research relating to the effectiveness of these modalities. In this review we analyze the available data that relates to the therapy of trigeminal neuralgia, postherpetic neuralgia, and posttraumatic neuropathies and provide clinical guidelines. The review focuses on medical management, as well as surgical and other interventions for painful neuropathies.
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