Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

MEG mapping in multiple sclerosis patients.

A Kotini1, P Anninos, D Tamiolakis

  • 1Laboratory of Medical Physics, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.

Europa Medicophysica
|March 24, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A comparative immunohistochemical investigation of the consequences of chorioamnionitis on the developing human fetal spleen.

Clinical and experimental obstetrics & gynecology·2018
Same author

Magnetoencephalography and normal pressure hydrocephalus: A case report.

Journal of integrative neuroscience·2018
Same author

Post-irradiation vaginal spindle cell sarcoma.

Pathologica·2017
Same author

MEG evaluation of pico-Tesla external TMS on multiple sclerosis patients.

Multiple sclerosis and related disorders·2016
Same author

Biomagnetic activity and non linear analysis in obstetrics and gynecology in a Greek population.

Clinical and experimental obstetrics & gynecology·2016
Same author

Pleural effusion cytology due to malignancy. A combined cytomorphological-immunocytochemical study of 500 cases.

Revista portuguesa de pneumologia·2016
Same journal

Beyond PubMed. Other free-access biomedical databases.

Europa medicophysica·2007
Same journal

Role of stretching in Charcot-Marie-Tooth disease.

Europa medicophysica·2007
Same journal

Rehabilitation and outcome measurement: where is Rasch analysis going?

Europa medicophysica·2007
Same journal

Functional assessment in rehabilitative medicine.

Europa medicophysica·2007
Same journal

Functional assessment in rehabilitation medicine: clinical applications.

Europa medicophysica·2007
Same journal

Untangling function: measuring the severity, type and meaning of disabilities.

Europa medicophysica·2007
See all related articles

Magnetoencephalography (MEG) revealed distinct brain activity differences in multiple sclerosis (MS) patients compared to controls. Abnormal rhythmic activity was observed in MS patients, suggesting a novel diagnostic approach.

Area of Science:

  • Neuroscience
  • Immunology
  • Biophysics

Background:

  • Multiple sclerosis (MS) is increasingly understood as an immune system disorder.
  • The pineal gland, regulating immunity via melatonin, influences brain regions like the hippocampus and cerebellum.
  • Investigating brain activity in MS patients may reveal disease-specific patterns.

Purpose of the Study:

  • To explore differences in brain activity between multiple sclerosis patients and healthy controls.
  • To utilize magnetoencephalography (MEG) for detecting these potential brain activity variations.
  • To establish a novel method for assessing brain function in MS.

Main Methods:

  • Magnetoencephalography (MEG) recordings were obtained from 10 MS patients and 10 controls.
  • Measurements used a superconducting quantum interference device (SQUID) in a shielded room.

Related Experiment Videos

  • Magnetic activity was recorded from 32 scalp points based on the International 10-20 Electrode Placement System.

    • Main Results:

    • Biomagnetic signals were analyzed for magnetic power spectral amplitudes in the 2-7 Hz range.
    • MS patients exhibited abnormal rhythmic brain activity with lower amplitudes and frequencies at certain points compared to controls.
    • A novel mapping technique, ISO-spectral amplitude scalp distribution, was developed using MEG data.

    Conclusions:

    • This preliminary study introduces a novel approach to measure brain biomagnetic activity in MS patients.
    • MEG can potentially differentiate brain activity patterns in MS.
    • Further research is warranted to validate this technique for MS diagnosis and monitoring.