Related Experiment Video
Updated: Jul 16, 2026

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
Published on: April 8, 2013
Outcomes following surgical ventricular restoration in elderly patients with congestive heart failure
Jason A Williams1, Nishant D Patel, Lois U Nwakanma
1Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD 21287-4618, USA.
Abstract:
Despite the well described benefits of surgical ventricular restoration (SVR) for patients with ischemic cardiomyopathy, the effects of advanced age on outcomes following this procedure have not been well documented. The authors compared outcomes in 69 consecutive patients 65 years and older (n=27) and younger than 65 years (n=42) to determine the utility of SVR in an elderly population with end-stage heart failure. Patients 65 years and older demonstrated significant improvements in ejection fraction (P=.01) and left ventricular end-systolic volume index (P=.07) following SVR, which were similar to the improvements seen in patients younger than 65 years. Sixty percent (15 of 25) of patients 65 years and older in preoperative New York Heart Association class III/IV improved to class I/II at follow-up (P<.0001). Actuarial survival was 68.8% at 2.5 years. Like their younger counterparts, elderly patients demonstrate significant improvements in ventricular function and NYHA class with acceptable survival following SVR.
Related Concept Videos
Cardiomyopathy V: Interprofessional Care
Heart Failure VI: Adjunct Therapies
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiomyopathy II: Dilated Cardiomyopathy
Heart Failure II: Pathophysiology
Heart Failure V: Medical Management

