Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nonconvulsive status epilepticus in the elderly: a case-control study.

F J Bottaro1, O A Martinez, M M Fernandez Pardal

  • 1Department of Internal Medicine, Buenos Aires British Hospital, Buenos Aires, Argentina. febottaro@hotmail.com

Epilepsia
|March 27, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reduction of photoparoxysmal response from patients with drug-resistant photosensitive epilepsy by using Z1 filters.

Neurologia·2022
Same author

Reduction of photoparoxysmal response from patients with drug-resistant photosensitive epilepsy by using Z1 filters.

Neurologia·2021
Same author

Fabry disease patients have an increased risk of stroke in the COVID-19 ERA. A hypothesis.

Medical hypotheses·2020
Same author

Comparison of media and growth conditions for culturing enterohepatic Helicobacter species.

Letters in applied microbiology·2019
Same author

[Gastroesophageal reflux as a cause of vocal dysfunction].

Anales de medicina interna (Madrid, Spain : 1984)·2009
Same author

Numb chin syndrome by biphosphonates.

European journal of internal medicine·2008
Same journal

Responsible use of artificial intelligence in peer-reviewed publications in epilepsy.

Epilepsia·2026
Same journal

Altered autonomic balance drives the increase in cardiac output and arterial pressure during convulsive seizures in nonanesthetized sheep.

Epilepsia·2026
Same journal

Diagnostic yield and copy number variants findings in 219 adult patients with developmental and epileptic encephalopathy.

Epilepsia·2026
Same journal

Prolonged fenfluramine use in open-label studies of Dravet or Lennox-Gastaut syndromes: Long-term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness.

Epilepsia·2026
Same journal

Electrocardiography characteristics and long-term mortality in people with epilepsy from a resource-poor community.

Epilepsia·2026
Same journal

Factors associated with rapid pediatric acute seizure emergency treatment: Quality Improvement in Time to Treat Status Epilepticus baseline cohort.

Epilepsia·2026
See all related articles

Nonconvulsive status epilepticus (NCSE) in elderly patients (>75 years) is often underdiagnosed. This condition leads to higher morbidity and worse prognosis compared to altered mental status without NCSE.

Area of Science:

  • Neurology
  • Geriatrics
  • Epileptology

Background:

  • Nonconvulsive status epilepticus (NCSE) is an underdiagnosed condition causing altered awareness in the elderly.
  • Early diagnosis and treatment are crucial for managing NCSE in older adults.

Purpose of the Study:

  • To assess the etiologies, comorbidities, and prognosis of NCSE in patients over 75 years old.
  • To compare NCSE patients with elderly individuals experiencing altered mental status without NCSE.

Main Methods:

  • A nested case-control study involving 19 elderly patients with NCSE and 34 controls.
  • Retrospective evaluation of clinical data, EEG findings, brain imaging, comorbidities, and outcomes.
  • Statistical analysis using chi-square, t-test, Fisher's exact, and Wilcoxon rank sum tests.

Related Experiment Videos

Main Results:

  • NCSE etiologies included epilepsy (2), acute medical disorders (14), and cryptogenic (4).
  • NCSE patients showed higher rates of prior epilepsy (35% vs 8.8%), tramadol use (31% vs 0%), longer hospitalizations (25 vs 7 days), and unfavorable outcomes (50% vs 5.8%).
  • Unfavorable outcomes were linked to >2 comorbidities and severely altered mental status.

Conclusions:

  • NCSE is a significant cause of altered mental status in the elderly, associated with increased morbidity.
  • While its direct role in brain damage is debated, NCSE negatively impacts prognosis in older adults.
  • NCSE necessitates prompt recognition and management in geriatric populations to improve outcomes.