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Bilateral S3 stimulator in patients with interstitial cystitis
Adam C Steinberg1, Ian A Oyama, Kristene E Whitmore
1University of Medicine and Dentistry of New Jersey/Robert Wood Johnson Medical School, Camden and Cooper University Hospital, Camden, New Jersey, USA. acsteinberg06@yahoo.com
Urology
|March 27, 2007
Summary
Bilateral sacral nerve stimulation significantly reduces urinary frequency and nocturia in interstitial cystitis patients, improving quality of life. This treatment also shows promise for alleviating fecal incontinence symptoms.
Area of Science:
- Urology
- Neuromodulation
- Pelvic Health
Background:
- Interstitial cystitis (IC) presents significant challenges, including urinary frequency, urgency, and pain.
- Sacral nerve stimulation (SNS) is an established treatment for lower urinary tract dysfunction.
- The efficacy of bilateral SNS for IC symptoms requires further investigation.
Purpose of the Study:
- To evaluate the effectiveness of bilateral S3 sacral nerve stimulators in managing interstitial cystitis symptoms.
- To assess patient-reported outcomes, including urinary distress and voiding patterns.
- To explore potential benefits for co-existing fecal incontinence.
Main Methods:
- Retrospective chart review of 15 patients undergoing bilateral S3 SNS implantation.
- Data collection included pre- and post-operative voiding diaries and the Urinary Distress Inventory (UDI-SF).
- Exclusion criteria: prior sacroneuromodulation, neurological deficits, or urinary retention.
Main Results:
- Significant reductions in urinary frequency (10.4 voids/day, P <0.001) and nocturia (2.6 voids/day, P <0.001).
- High patient satisfaction reported postoperatively via the UDI-SF (P <0.001).
- Four patients experienced improvement in fecal incontinence episodes (mean decrease of 2.75, P <0.01).
Conclusions:
- Bilateral sacral nerve stimulation offers a valuable therapeutic option for interstitial cystitis.
- The procedure leads to significant improvements in urinary frequency, nocturia, and overall patient satisfaction.
- Potential benefits for fecal incontinence warrant further research.
