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Updated: May 5, 2026

Unraveling the Unseen Players in the Ocean - A Field Guide to Water Chemistry and Marine Microbiology
Published on: November 5, 2014
Argonautes and company: sailing against the wind
Suvendra N Bhattacharyya1, Witold Filipowicz
1Friedrich Miescher Institute for Biomedical Research, 4002 Basel, Switzerland.
Abstract:
The 3'-untranslated region (UTR) of mRNA is crucial for posttranscriptional regulation. In this issue, Vasudevan and Steitz (2007) report a new function for AGO2 and FXR1--two proteins that have been linked to the regulation of microRNAs and translation repression. AGO2 and FXR1 bind to the AU-rich element in the 3'-UTR of TNFalpha mRNA, unexpectedly activating its translation in a cell growth-dependent manner.
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