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Updated: Jul 16, 2026

Recombineering Homologous Recombination Constructs in Drosophila
Published on: July 13, 2013
Understanding the biases of generalised recombination: part II
Riccardo Poli1, Christopher R Stephens
1Department Computer Science, University of Essex, Colchester, UK. rpoli@essex.ac.uk
Abstract:
This is the second part of a two-part paper where we propose, model theoretically and study a general notion of recombination for fixed-length strings where homologous recombination, inversion, gene duplication, gene deletion, diploidy and more are just special cases. In Part I, we derived both microscopic and coarse-grained evolution equations for strings and schemata for a selecto-recombinative GA using generalised recombination, and we explained the hierarchical nature of the schema evolution equations. In this part, we provide a variety of fixed points for evolution in the case where recombination is used alone, thereby generalising Geiringer's theorem. In addition, we numerically integrate the infinite-population schema equations for some interesting problems, where selection and recombination are used together to illustrate how these operators interact. Finally, to assess by how much genetic drift can make a system deviate from the infinite-population-model predictions we discuss the results of real GA runs for the same model problems with generalised recombination, selection and finite populations of different sizes.
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